Scientists Discover a Cause of Lupus, Possible Way to Reverse It

Re:Scientists Discover a Cause of Lupus, Possible Way to Rev... by roywiggins on Wednesday July 10, 2024 @07:06PM (#40932346)

There is evidence that inflammation is among the causes of depression:

https://wapo.st/3xHLze1

> pro-inflammatory drugs can induce people to become depressed, which suggests a causative link. In one seminal study published in the New England Journal of Medicine, Miller and his colleagues conducted a double-blind study of 40 cancer patients undergoing treatment with interferon-alpha, an inflammatory cytokine.

> Though none of the patients had depression to begin with, the inflammatory agent had a striking effect: Many became depressed, a finding that has been consistently replicated.

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Re:Scientists Discover a Cause of Lupus, Possible Way to Rev... by Aerroon on Wednesday July 10, 2024 @10:58PM (#40933316)

Is this why something like vitamin C can help with depression?

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Re:Scientists Discover a Cause of Lupus, Possible Way to Rev... by theGnuMe on Thursday July 11, 2024 @12:10AM (#40933622)

[delayed]

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Re:Scientists Discover a Cause of Lupus, Possible Way to Rev... by sharpshadow on Thursday July 11, 2024 @07:45AM (#40935618)

„Vitamin C supplementation attenuates the oxidative stress (lipid peroxidation) and inflammatory response (IL-6) to a single bout of exercise.“[1]

Vitamin C is essential and gets consumed by the body and needs to be replenished. For example during sickness the Vitamin C consumption is higher which could lead quickly to low levels.

1. https://pubmed.ncbi.nlm.nih.gov/32162041/

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Re:Scientists Discover a Cause of Lupus, Possible Way to Rev... by lyall on Thursday July 11, 2024 @12:49AM (#40933757)

I don’t believe there is any evidence that vitamin C reduces inflammation or helps with depression. Vitamin C is an antioxidant, not an anti-inflammatory agent.

There is evidence that things that reduce systemic inflammation help with depression. Fish oil, or more generally a balanced omega-3/omega-6 intake is one example. Curcumin is another. However the effects are modest, which is probably to be expected with a condition as diverse as depression.

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Re:Scientists Discover a Cause of Lupus, Possible Way to Rev... by funnym0nk3y on Thursday July 11, 2024 @07:41AM (#40935582)

However the causality is not clear. Inflammatory agents cause depression. And most depressed people have higher pro-inflammatory markers. It could also be the case that the inflammation is a result of something completely different.

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