Rye is perfectly fine to use as of now. It uses uv under the hood anyway, but has some niceties of its own.

For example?

Poetry.

I would.

I would use Uv - if you can handle that it's a moving target right now. (uv python, uv lock, uv sync and so on, and in pyproject tool.uv.sources). All preview features that replace similar Rye features with a more robust implementation.