You can run double-bind studies on yourself, if you are curious.

Gwern is famous for running lots of self-blinded experiments on himself.

Makes me wonder if there's a risk of losing a placebo effect by knowing it's a placebo effect.

We know that placebo can work even if you tell the person that they're taking a placebo. The placebo effect is so famous that people already expect a benefit from it.

But I guess it varies by individuals so maybe some people would lose it.

Now, designing a controlled experiment to investigate that claim is a good challenge!

Hmmm, I have no idea how to get or make the placebo pills, I don't have any tools to make them myself, I wonder if my pharmacy or a local lab would accept to do it for me. I might actually do that but I would need to try two cures instead of a random pill every day because I currently start "feeling better" after a few weeks of taking it.

I am actually curious enough to try it but I would need to do it next semester or next year because I would need to also buy or secure enough multivitamins for the year (two cures a year, it would not be a double blind anymore if I get them just before the cure) and since some of them are prescription I'll have to talk about it with my doctor, see if he would prescribe enough and if yes, how long is their shelf life and how I would go to get placebos.

You can buy empty capsules that you can fill yourself.

So you fill some inert powder into the placebo capsules, just so they have the same weight as the one you crush your non-placebo in.

I am also taking to prevent petty non-dangerous diseases or to raise some aspects of my everyday life above baseline, where the baseline is the ballanced diet (yet not rich in some ingredients by nature). Not to mention counter ballancing one prescription medicine's side effect. Basically for quality of life and for feeling good, not to avoid death. : )

Pretty much this (and it was doctor prescribed - as much as this might be debatable)

Life is not just how many years you live, or rigid classifications of diseases