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A comment on Ozempic keeps wowing: trial data show benefits for kidney disease. Parent comment

Re:Ozempic keeps wowing: trial data show benefits for kidney... by MrPoush on Friday May 24, 2024 @07:28PM (#40471385)
It's not the only drug that suppresses appetite, but GLP-1 agonists (Ozempic, Zepbound, etc) appear to work for a larger percentage of the population, and significantly outperform previous appetite suppressants.

There's also findings that suggest that it goes beyond simply suppressing appetite, but also manipulates the "reward" center in the brain. Individuals who take it to lose weight find that they have reduced desire to drink or smoke, suggesting it's less that they struggle with appetite and more the medicine helps overcome addictive behavior.

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Re:Ozempic keeps wowing: trial data show benefits for kidney... by andrewinardeer on Friday May 24, 2024 @10:29PM (#40472200)
Nicotine suppresses appetite as well and that has been used by humans for thousands of years.
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Re:Ozempic keeps wowing: trial data show benefits for kidney... by raydev on Saturday May 25, 2024 @01:06AM (#40472780)
Sure, it's just not as good as Ozempic at doing that particular job.
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Re:Ozempic keeps wowing: trial data show benefits for kidney... by solumunus on Saturday May 25, 2024 @07:49AM (#40474346)
That’s so silly, these drugs aren’t even anywhere near the same league of effectiveness. There’s plenty of fat people who take nicotine all day.
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Re:Ozempic keeps wowing: trial data show benefits for kidney... by datavirtue on Saturday May 25, 2024 @10:02AM (#40475131)
Hmmm...if as many people consumed semeglutide you would have examples of fat people in that population as well.
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Re:Ozempic keeps wowing: trial data show benefits for kidney... by eganist on Saturday May 25, 2024 @10:34AM (#40475298)
You certainly would, because not every case of obesity results from the same mechanisms. But just as with all the other what-about comments, this comment misses the point: this class of drug is wildly successful, and it's the most specific drug for this problem that's been developed so far

https://www.healthline.com/health-news/ozempic-glp-1-drugs-m...

Here's a good piece running through the failure modes in lay terms.

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Re:Ozempic keeps wowing: trial data show benefits for kidney... by solumunus on Sunday May 26, 2024 @12:09PM (#40483238)
This is genuinely one of the stupidest conversations I’ve been involved in. If nicotine was as effective as Ozempic at appetite suppression then everyone would know about it, it would be commonly used in medicine to treat obesity and Ozempic would never have been created. I hope for your sake this is pedantry instead of ignorance.
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