For example, I consult, and while in principle I could attempt to sell anyone with authority to write a check on consulting engagements, I don't. If I meet someone at a party and he says "I don't have a website but..." there is no possible end to that sentence whatsoever under which he is a good prospect for business in the near term. If you want a Rails programmer? Nope, sorry, I'm probably not your guy. If you're a software company with $10k in the bank, you can't afford a formal engagement with me. Strongly qualified leads for me tend to, e.g., have over 10 employees, profitable software businesses with revenue in the millions to tens of millions, multiple opportunities for things I can do for them, a business model which suggests ample opportunity for positive ROI at the rates I charge, and some reason to have personal trust for me.
To the extent that I do active sales work (e.g. flying out to a city to meet with your CEO, creating proposals, etc), I focus my active sales work on qualified leads, rather than "any business I could possibly think of."
Applying this to a job search: he's sending resumes to places which are not hiring. That isn't a strongly qualified lead. That's like me soliciting five figure checks off every passerby in Ogaki Station. Total waste of time.
So I think Patrick is arguing that more qualification is necessary - it sounds like employers are seeing this resume as a low quality lead. Meet some people who can help you, do something that tells an employer "this person might make me more money!", etc.
Operationally, answering the question: "Are you selling what they are looking to buy?"
The more sense it makes for both parties, the higher the probability for the deal to get into more advanced stages.