We humans just like good engaging stories, even if they are not always realistic.
Even deep space maneuvers can be done manually if you know what you are doing - point ship engines in right direction and thrust for right number of seconds/minutes.
Sure, for stuff like orbital launch, some crazier Oberth effect burns or continuous thrust propulsion (ion, solar sail) you definitely want computer control.
I can see an argument for manual landing on another cosmic body, given the famous story of Neil Armstrong saving Apollo 11 landing by manually landing the capsule. Though the latest generation of lunar landers can perform the procedure fully autonomously, using machine vision to find an optimal landing spot.
I tried looking up, whether manual or automated moon landing is planned for HLS program, but couldn't find anything specific. It's probably going to be some mix of both.