IMO one thing worth considering is the amount of muscle loss that occurs during regular rapid weight loss -- not enough studies have done comparison (I assume since it's very hard to induce the latter state).
It is interesting to think about the possibility that rather than decreasing the amount people go to the gym, GLP1 Receptor Agonists (Ozempic, Wegovy, Mounjaro, Zepbound, etc) might increase it.
I've written a little bit about this here[0], and while I don't always cite YouTube doctors, Doctor Mike Hansen has a pretty good evidence-heavy take[1].
For example one thing he gets into is that Tirzepatide (ex. Zepbound, Mounjaro -- the only one FDA approved for weight control) is more successful at fat loss relative to Semaglutide (ex. Ozempic, Wegovy, Rybelsus).
https://www.nejm.org/doi/full/10.1056/NEJMoa2206038
https://www.nejm.org/doi/full/10.1056/NEJMoa2032183
IMO one thing worth considering is the amount of muscle loss that occurs during regular rapid weight loss -- not enough studies have done comparison (I assume since it's very hard to induce the latter state).
It is interesting to think about the possibility that rather than decreasing the amount people go to the gym, GLP1 Receptor Agonists (Ozempic, Wegovy, Mounjaro, Zepbound, etc) might increase it.
I've written a little bit about this here[0], and while I don't always cite YouTube doctors, Doctor Mike Hansen has a pretty good evidence-heavy take[1].
For example one thing he gets into is that Tirzepatide (ex. Zepbound, Mounjaro -- the only one FDA approved for weight control) is more successful at fat loss relative to Semaglutide (ex. Ozempic, Wegovy, Rybelsus).
[0]: https://glp1.guide/content/can-glp1-drugs-replace-diet-and-e...
[1]: https://www.youtube.com/watch?v=ScBx37MBZ2s