ForceGen: End-to-end de novo protein generation

Re:ForceGen: End-to-end de novo protein generation by BenFranklin100 on Saturday February 10, 2024 @11:19PM (#39332616)

This is an interesting and novel paper. Speaking as a biophysicist, I see potential applications in the regenerative medicine space with cartilage and/or joint replacement. There could be also applications in the field of dermatology with aging therapies or skin grafts. More speculatively, one can imagine scientists developing superior types of joints or connective tissues than the ones evolution has landed upon.

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Re:ForceGen: End-to-end de novo protein generation by instagraham on Sunday February 11, 2024 @09:29AM (#39335198)

A question for any novel approach like this - every single usecase needs its own safety and clinical trial before we can see it in action on humans?

Anything this synthesizes will have a 10-15 year minimum waiting period, I assume?

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Re:ForceGen: End-to-end de novo protein generation by BenFranklin100 on Sunday February 11, 2024 @10:11AM (#39335500)

I estimate at least 20 years before we see practical applications. Biology is complicated, developing effecting therapies often even more so. But we have to start somewhere.

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