Rye[1] is an all in one manager for python projects. Including the python versions and virtualenv, pip etc etc... It separates tool deps from app deps. Its all configured through a pyproject.toml config file.

Its still new but works well. I'm transitioning to it from an unholy mess of pyenv, pip installs and other manual hacks.

If you're starting a new python project that is more than just a straightforward script I'd use Rye from the get go.

[1]https://rye-up.com/