I think about all the apps I'm running and switching between on my computer now, using shortcuts and toolbars and docks to arrange, hide, and switch between them. Everyone using multiple apps on visionOS just looks chaotic.
I once had a second portrait monitor next to my ultrawide. I had to get rid of it because it was just too tiring to be constantly turning my head so far to look at it. It didn't work out.
I cannot imagine how uncomfortable it would be if each app needed to be in a different physical space that required turning my head to use. Painful.
At a deeper level it depends a lot on the question of does Apple want this? If they do then all these will be solved over time. But if they actually see MacOS as a legacy integration then they simply aren't going to invest in encouraging people to use it. I'm waiting to see indications on which way they are going to play it.