>Increased heat wave intensity and frequency, increased humidity, degraded air quality, and reduced water quality will increase public health risks.

>More than 20 million people in the Midwest already breathe air that fails to meet national ambient air quality standards.

>Air quality is expected to get worse with higher temperatures, due to both human-induced emissions and longer pollen seasons.

>The frequency of major heat waves in the Midwest has increased over the last six decades. Between 1980 and 2010, the rate of warming in the Midwest increased three times as quickly as it did from 1900 to 2010.

>Extreme rainfall events and flooding have increased during the last century, and these trends are expected tocontinue across the entire region. In the Midwest, when it rains, it will – more and more frequently – pour.

What about that "plentiful fresh water supply"?

>These lake surface temperatures are projected to rise by as much as 7°F by 2050 and 12.1°F by 2100.

>Higher temperatures, increased precipitation, and lengthened growing seasons are likely to result in increased production of blue-green and toxic algae in the lakes. Blooms of these algae can harm fish, water quality, habitats, and aesthetics—and could worsen the impact of invasive species.[1]

[0]https://www.edf.org/sites/default/files/content/regional_rel...

[1]https://toolkit.climate.gov/regions/great-lakes