> What signals cause rewiring of the cerebellum?

Any signal, that's the point. The cerebellum learns the patterns of signals involved in motor control.

This is why you train your skills by doing the correct movement over and over again. Once the cerebellum has adjusted to the correct motor signal patterns the correct movement will become effortless.

> This is why you train your skills by doing the correct movement over and over again.

Yes, but can you make this to go faster?

You'd have to apply an adverse stimulus in under a ~5ms threshold to actions that were 'wrong'. It would depend on the exact task you're trying to do though. That would then cause other areas to potentiate that specific movement/firing as incorrect.

Its a active area of research in sports and DoD. As you'd theoretically be able to train marksmen and athletes at a much faster and better rate. However, even really really fast computers aren't quite fast enough to apply the adverse stimulus to 'wrong' movements/firing.

Also, your computer better be really accurate and never mess up, or that person is going to have a hell of a time retraining their brain. Also, their brain may view that the clouds/temperature/itchy grass/breakfast are the reasons for the adverse stimulus, as this is all happening at in subconscious time frame. So, good luck there.

This is great info, thanks!

Pain or satisfaction, probably.

When a motion "feels good", or is painful, probably means you learn. So chase those.

Train harder. Develop habits.

I think we're in the "punch card" phase of biology. I'd be willing to bet (timeline uncertain) that there will be shortcuts to this process.

For now, opportunity cost rules the day. I'm 120% maxed out.

The pattern of muscle activation timing in the correct move form needs to be figured out by exploration of the space.

We don't typically efficiently explore the space. This is why coaches exist.

The feedback loops are often long. Getting a review on a performance, etc.

If a device were set up to trigger pain within some milliseconds of an incorrect activation, surely we could speed this up?

I’m going to say it’s all about the glutamate.

https://www.nature.com/articles/s41467-023-38475-9

Psilocybin and other psychedelics may be that exogenous agent, they release Brain-derived neurotrophic factor (BDNF) [0], which plausibly could cause “rewiring of the cerebellum” [1][2], and may even do this with sub-perceptible (micro)doses [3].

[0] https://pubmed.ncbi.nlm.nih.gov/37280397/

[1] https://www.nature.com/articles/s41386-022-01389-z

[2] https://www.frontiersin.org/articles/10.3389/fpsyt.2021.7246...

[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8033605/