Noe valley, Cole Valley, Inner Sunset, Inner Richmond, most of pacific heights / Marina, Russian hill, all of the southwest neighborhoods if you want a more suburban experience, Excelsior / Glen Park / Bernal as well are all pretty safe neighborhoods, even more so a block from the commercial strips.

SF is a block by block affair though, there’s a few sketchy blocks in all of those neighborhoods, you just have to know the social topology of the city.