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A comment on Nicotine: On the benefits and lack of demerits of nicotine. Parent comment

Re:Nicotine: On the benefits and lack of demerits of nicotine by vGPU on Saturday November 11, 2023 @12:42PM (#38232509)
Not particularly. Pure nicotine in and of itself is significantly less addictive than the form presented in a cigarette. Modern big tobacco has managed to create an incredibly nasty and addictive chemical slurry in a stick, with acetaldehyde, ammonia, MAOIs, and a bunch of other chemicals which significantly increase the addictiveness of nicotine.

Gwern has noted the same in his post:

> Wikipedia summarizes Guillem et al 2005 as “Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties” - the addictiveness coming from MAOIs (eg. Khalil et al 2000, Khalil et al 2006) & possibly other compounds present in tobacco

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Re:Nicotine: On the benefits and lack of demerits of nicotine by vGPU on Saturday November 11, 2023 @01:00PM (#38232703)
Gwern has noted the same in his post:

> Wikipedia summarizes Guillem et al 2005 as “Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties” - the addictiveness coming from MAOIs (eg. Khalil et al 2000, Khalil et al 2006) & possibly other compounds present in tobacco

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Re:Nicotine: On the benefits and lack of demerits of nicotine by ShamelessC on Saturday November 11, 2023 @05:07PM (#38235061)
Gwern has noted the same in his post:

> Wikipedia summarizes Guillem et al 2005 as “Technically, nicotine is not significantly addictive, as nicotine administered alone does not produce significant reinforcing properties” - the addictiveness coming from MAOIs (eg. Khalil et al 2000, Khalil et al 2006) & possibly other compounds present in tobacco

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Re:Nicotine: On the benefits and lack of demerits of nicotine by vGPU on Monday November 13, 2023 @11:34AM (#38252079)
It wasn’t showing up when I had edited initially, my bad.
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