But to answer the question, the danger of AI is uniquely relevant because it is the only danger that may end up being totally out of our control. Nukes, pandemics, climate change, etc. all represent x-risk to various degrees. But we will always be in control of whether they come to fruition. We can pretty much always short circuit any of these processes that is leading to our extinction.

A fully formed AGI, i.e. an autonomous superintelligent agent, represents the potential for a total loss of control. With AGI, there is a point past which we cannot go back.