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A comment on Disappearing Polymorphs.

Re:Disappearing Polymorphs by swarthout on Monday October 30, 2023 @12:03AM (#38065544)
It is wild to see disappearing polymorphism appear on the front page of HN! My company, Lavo Life Sciences (W23) is building software to predict polymorphism in drug molecules, happy to answer any questions on this thread :)
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Re:Disappearing Polymorphs by xvedejas on Monday October 30, 2023 @12:15AM (#38065613)
Are there any promising paths towards preventing this? Seeding clean rooms with other chiral molecules that can encourage the lost higher energy form of a crystal, maybe?
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Re:Disappearing Polymorphs by izme on Monday October 30, 2023 @12:17AM (#38065629)
It also makes you wonder if novel crystal forms could be discovered by purposely seeding the process with other arbitrary seeds.
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Re:Disappearing Polymorphs by greggsy on Monday October 30, 2023 @11:17AM (#38070510)
I wonder if you could also detect it using some other harmless but otherwise volatile material?
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Re:Disappearing Polymorphs by Izkata on Monday October 30, 2023 @01:43PM (#38072843)
I think there was another post about this a few days ago. IIRC the title was about a specific drug affected by it.
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