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Re:Pepper X by _a_a_a_ on Friday October 20, 2023 @05:33AM (#37954008)
There is a euphorbia (a hoodia? can't recall reference) with a chemical 500 times stronger than capsaicin. IIRC so strong it destroys the receptor.

Anyone have a ref while I paw through my memory slowly?

Re:Pepper X by resolutebat on Friday October 20, 2023 @06:27AM (#37954366)
Bonus: RTX has also previously been investigated as a treatment for lifelong premature ejaculation (PE).. Volunteers for clinical trials, anyone?
Re:Pepper X by ceejayoz on Friday October 20, 2023 @08:53AM (#37955384)
Jesus. I hope that's administered while you're in an induced coma.
Re:Pepper X by 4oo4 on Friday October 20, 2023 @05:11PM (#37961590)
Someone actually concentrated and taste tested some of this in a fairly scientific process, and it actually didn't end up being as hot as expected. iirc the molecule is too big to properly bind to receptors the way capsaicin can.

https://www.youtube.com/watch?v=XPe2bssalOY