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A comment on Ketamine's effect on depression may hinge on hope. Parent comment

Re:Ketamine's effect on depression may hinge on hope by astrange on Friday October 20, 2023 @01:55AM (#37952761)
There's also reliable studies that it isn't that, and I actually expect it isn't, since antidepressants in general don't work by making you introspect. Actually "rumination" is a symptom of depression, so they would make you do it less, and IME meditation is not about introspection either.

Here's one showing a mechanism ketamine and antidepressants both act on:

https://www.science.org/content/blog-post/how-antidepressant...

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Re:Ketamine's effect on depression may hinge on hope by omginternets on Friday October 20, 2023 @03:32PM (#37960485)
Discussion of psychadelics often concern themselves with recurring or treatment-resistant depression, so the transcendental analysis is very relevant.

Depression seems to have more than once cause.

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