Yes. Some vendors allow you to control the sugar content, at least. I had ordered a drink with "light" sugar once (1/4 of normal amount) and it still tasted plenty sweet to me, and probably still topped at 350-400 calories. I usually never drink my calories.
And plenty of studies have linked excess sugar with depression [1]
[1]: https://www.webmd.com/diet/what-to-know-about-sugar-and-depr....