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A comment on Life-changing cystic fibrosis treatment wins US$3M Breakthrough Prize. Parent comment

Re:Life-changing cystic fibrosis treatment wins US$3M Breakt... by Scoundreller on Saturday September 16, 2023 @10:51PM (#37541035)
In my opinion orlistat (blocks fat absorption) isn't that bad if you actually follow the suggested low-fat diet. But if you're hoping to counteract a pint of ice cream, it's going to work tooooo well. The Public Relations was a nightmare... never stood a chance. The jokes were too good.
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Re:Life-changing cystic fibrosis treatment wins US$3M Breakt... by arthur2e5 on Sunday September 17, 2023 @02:03AM (#37541982)
Acarbose blocks starch (and sucrose, to some extent) absorption. Instead of oily poop you get gas that hopefully goes down over time. Starch & sucrose is not as big a part of American caloric intake as fat, but it can still help a bit.

(Just sucrose. HFCS has glucose and fructose, which means sucrase doesn't need to work. Not a meaningful difference in most people considering how fast sucrase works, but when you block sucrase...)

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