Re:Vaccine Reverse Multiple Sclerosis, Type 1 Diabetes, and ...
by olliej on Thursday September 14, 2023 @12:56PM
(#37511511)
Can’t tell from the article whether this in mice, in a plate, or simply in theory?
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Re:Vaccine Reverse Multiple Sclerosis, Type 1 Diabetes, and ...
by kieranmaine on Thursday September 14, 2023 @01:08PM
(#37511695)
The referenced study https://www.nature.com/articles/s41551-023-01086-2 says "a mouse model" and "non-human primates":
"We show that pGal–antigen therapy induces antigen-specific tolerance in a mouse model...as well as the suppression of antigen-specific responses to vaccination against a DNA-based simian immunodeficiency virus in non-human primates"
The article also mentions that phase I trials have been carried out with humans:
"initial phase I safety trials have already been carried out in people with celiac disease...and phase I safety trials are underway in multiple sclerosis"
Re:Vaccine Reverse Multiple Sclerosis, Type 1 Diabetes, and ...
by olliej on Thursday September 14, 2023 @02:06PM
(#37512556)
Thanks! I didn't think to search for "phase" despite that being an obvious term when wondering about trials.