Re:The human Y chromosome has been completely sequenced
by robwwilliams on Friday August 25, 2023 @09:09AM
(#37261278)
Not true now with PacBio Revio and new Oxford Nanopore chemistry and flow cells. We still use a bit of older Illumina data for polishing, but long read methods now as accurate. HiC and Bionano more important as supplements than 150 nucleotide pair-end reads.
And the cost of a T2T using a combination of these technologies is already well under $10,000 in reagent costs. The assembly is still a complex art especially for a messy chromosome like Y.
And the cost of a T2T using a combination of these technologies is already well under $10,000 in reagent costs. The assembly is still a complex art especially for a messy chromosome like Y.