I think this is highly dependent on what your beliefs are pre-trip and how you define what makes you you. I've had many psychedelic experiences and while I often feel greater connection to living things around me, I've never been left with the feeling that my "soul" or anything I'd define as me will exist when I'm gone.

This is congruent with the sense that my ‘soul’ is a local aspect of the dynamics that have been playing out in the universe and will continue after my death. I am a little piece of the dance, for a while.

That works for me.

Sure, but you have no more evidence of that sort so what's the point? Get high if you want but it's not going to tell you anything.