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A comment on Electrogenetic interface to program mammalian gene expression by direct current.

Re:Electrogenetic interface to program mammalian gene expres... by lwansbrough on Sunday August 06, 2023 @04:38AM (#37020081)
> In a proof-of-concept study in a type 1 diabetic male mouse model, a once-daily transdermal stimulation of subcutaneously implanted microencapsulated engineered human cells by energized acupuncture needles (4.5 V DC for 10 s) stimulated insulin release and restored normoglycemia.

Borderline unreadable sentence for a lay person like me but the implications of this are awesome.

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Re:Electrogenetic interface to program mammalian gene expres... by jncfhnb on Sunday August 06, 2023 @07:41AM (#37020954)
They stabbed injected human cells under the skin with an electric acupuncture needle to undo diabetes.
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Re:Electrogenetic interface to program mammalian gene expres... by FollowingTheDao on Sunday August 06, 2023 @09:20AM (#37021609)
They didn’t undo diabetes, they stimulated the release of insulin. You don’t undo diabetes (type 2) by releasing insulin.

And since releasing insulin only creates more insulin resistance by changing receptor density, this is just making it worse.

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Re:Electrogenetic interface to program mammalian gene expres... by jncfhnb on Sunday August 06, 2023 @09:24AM (#37021652)
If you can reliably release insulin you’ve more or less treated type 1 diabetes though.

Regardless, shrug.

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Re:Electrogenetic interface to program mammalian gene expres... by jwalgenbach on Sunday August 06, 2023 @11:39AM (#37023101)
The treatment is for type 1, not type 2. Very different causes.
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Re:Electrogenetic interface to program mammalian gene expres... by amelius on Sunday August 06, 2023 @08:54AM (#37021400)
If one human cell requires a voltage of 4.5V, then how much voltage should be applied to an entire human considering the cells are in series?
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Re:Electrogenetic interface to program mammalian gene expres... by anshukg on Sunday August 06, 2023 @11:45AM (#37023156)
This article simplifies it a bit : https://medium.com/@1kg/aa-battery-to-replace-your-meds-fbd6...
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