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Re:Sex-specific differences in myocardial injury after Covid... by greatfilter251 on Sunday July 30, 2023 @02:51PM (#36934636)
Great, more ridiculous anti-vaxx content on HN. I believe in science, which has definitively shown that vaccines are safe and effective. Even if there's a tiny increase in inflammation (which is doubtful: if this were real it would have been caught during clinical trials and yet nothing like this was observed), it's nothing compared to the risks of catching COVID.
Re:Sex-specific differences in myocardial injury after Covid... by tmn on Sunday July 30, 2023 @03:37PM (#36935081)
What specifically makes this study anti-vaxx? Science is an ongoing process and it’s unambiguously unscientific to be closed off to new information.

I understand the conspiratorial narratives on Covid are tiring, but this does not seem to be the study to project onto.

Perhaps I’m missing something from my quick read of the study.

Re:Sex-specific differences in myocardial injury after Covid... by yellowapple on Sunday July 30, 2023 @04:10PM (#36935410)
If this is "antivax", then it's only pretty mildly such:

> mRNA-1273 vaccine-associated myocardial injury was more common than previously thought, being mild and transient, and more frequent in women versus men. The possible protective role of IFN-λ1(IL-29) and GM-CSF warrant further studies.

A mild and temporary case of inflammation - affecting the exact opposite demographic the antivaxxers harped upon - is hardly some vindication of the antivax cause. A vaccine having side effects ain't mutually exclusive with it being safe and effective.

Re:Sex-specific differences in myocardial injury after Covid... by Gibbon1 on Sunday July 30, 2023 @06:53PM (#36936844)
It's totally anti-vax or paranoiac because if these were studies about some other drug side effect no one but no one would care at all. Even a doctor that treats patients with a drug with a similar side effect would just completely lose interest when he reads that the rate is a few per million and it resolves itself.

Doesn't help the anti-vaxers and paranoiacs can't be reasoned with at all.

Re:Sex-specific differences in myocardial injury after Covid... by yellowapple on Sunday July 30, 2023 @09:19PM (#36937852)
That all has nothing to do with this study (or its findings) and everything to do with antivaxxers being intellectually dishonest.
Re:Sex-specific differences in myocardial injury after Covid... by lockhouse on Sunday July 30, 2023 @04:11PM (#36935429)
The vaccines have been ineffective at preventing infection from COVID. There is evidence that they reduce the severity of symptoms when you do catch it, but it does nearly nothing to prevent infection with COVID.

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-...

Re:Sex-specific differences in myocardial injury after Covid... by yellowapple on Sunday July 30, 2023 @04:25PM (#36935575)
Prevention ain't some binary absolute. It's a matter of reducing viral load, which in turn reduces both severity of symptoms (often to the point of nonexistence) and the likelihood of retransmission. Would you say that life vests are "ineffective at preventing drowning" just because some people drown despite wearing life vests?
Re:Sex-specific differences in myocardial injury after Covid... by lockhouse on Sunday July 30, 2023 @06:30PM (#36936662)
We were told in no uncertain terms that this vaccine was 95% effective at preventing COVID and there were no side effects. Now all of a sudden the authorities are sheepishly admitting, no, it's not anywhere near 95% effective and it just reduces symptoms of COVID to more manageable levels. So I'm not surprised to hear that they lied about there being no side effects.

Just so you know, the FDA wanted 55 years to comply with a FOIA request related to the vaccines, so that seems a bit suspicious to me. Almost like they have some things to hide.

https://www.reuters.com/legal/government/wait-what-fda-wants...

Re:Sex-specific differences in myocardial injury after Covid... by yellowapple on Sunday July 30, 2023 @07:05PM (#36936936)
> We were told in no uncertain terms

By whom? I don't recall any actual authorities speaking in such absolutes. (Laypersons and journalists and politicians, on the other hand...)

> So I'm not surprised to hear that they lied about there being no side effects.

"We don't know of any side effects at this time" (even assuming that was ever said, which it wasn't; soreness, allergic reactions, fatigue, etc. were known and declared as side effects since pretty much day 1) is not a lie, even if it's discovered later that there might be some (additional) side effects.

> Just so you know, the FDA wanted 55 years to comply with a FOIA request related to the vaccines, so that seems a bit suspicious to me. Almost like they have some things to hide.

Or almost like going through 329,000 pages of documentation to redact confidential information (including PII) takes awhile, and that the FDA has other FOIA requests to handle on top of that.

Re:Sex-specific differences in myocardial injury after Covid... by xyzzy123 on Sunday July 30, 2023 @04:16PM (#36935485)
The details matter, beyond the "safe and effective!" catchphrase.

Vaccinate teenagers? kids? Babies? One shot? Four shots? Seasonal boosters? Should 30 yos take the same shots as a 75yo? Are antibody-only studies good at measuring "effectiveness" vs looking at patient outcomes?

There's like a million interesting questions here.

Re:Sex-specific differences in myocardial injury after Covid... by barbacoa on Sunday July 30, 2023 @05:21PM (#36936120)
>Even if there's a tiny increase in inflammation (which is doubtful: if this were real it would have been caught during clinical trials

I'm reminded here of what happened with Vioxx. When the clinical studies showed a dangerous increased risk of heart attacks, Merck simply falsified their data to remove those data points. It's estimated that 10000s of people died as a result of taking the drug. Some estimates even top 100000 deaths in the USA alone.

Also it wasn't exactly a tiny increase, the study puts the figure at 2.8% or 1 in 35 people had myocardial injury.