Imho: out-of-control capitalism, and the resulting wealth inequality with all its negative effects.

Ok, the world obviously isn't (yet) ready for a Star Trek style utopia where money isn't important & people work 'for the common good of humanity'.

And yes, globalized capatalism has served humanity well to make efficient use of resources, innovate, and drive down the cost of mass produced items to near-zero.

But conditions have changed. GDP is a poor yardstick for measuring a population's overall well-being. Nor need I explain how greedy corporations & their advertising has enshitified the web. Or how much human talent is wasted when poor people can't afford a proper education, their lives wasted in sweatshops making cheap T-shirts.

Going forward, we need something better as a base for our economies. 'Capitalism 2.0'? A good pinch of socialism? Universal basic income? Bhutan style GNH?

https://en.wikipedia.org/wiki/Gross_national_happiness

I don't have the answers. But 1 thing is for sure: free-wheeling capitalism in the form of multinational corporations creating 'shareholder value', is NOT it.