With open source CRM I'd guess there are improvements or derivatives that you'd want to protect under AGPL, but then there are also "configurations" where it's adapted to a user's business and tech as mentioned. Having to release the source for these would be a non-starter for many. It would be nice if there was a way to make a clear distinction between how the two are licensed, though there is some gray area it may be hard to cover, ie when is it a new feature vs a configuration.