If they have a single app/app suite that does everything, then sure that's fine (as long as it isn't things like copying a lot of data off an SD card or whatever) - the OS doesn't get involved much.

That isn't a common use case unless someone is paying a ton of money for a single, specialized piece of software that does everything they want, and the iPad only is used for that one thing. Which is a very limited subset of 'work'.