If you haven't moved yet, and are open to giving SF another chance, pick a new neighborhood. Based on your post, I'm guessing you lived in SoMa? It's... kinda the worst, honestly. I moved to the Dogpatch right before the pandemic (from SoMa) and am fantastically happy. The pandemic did kill a few businesses, but others have sprouted up in their place.

If the Dogpatch isn't your cup of tea, there are many other neighborhoods that are much safer, cleaner, and pleasant to live in than SoMa or thereabouts.