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Re:The Rise and Fall of Evidence Based Medicine (1998) [pdf] by haldujai on Saturday June 03, 2023 @06:15AM (#36175304)
Unopposed estrogen (i.e. the old estrogen only HRT) is bad for women of all sizes, endometrial cancer sucks.

Separately, obesity causes higher system estrogen levels and carries the same risks.

What you may be referring to is the more recent WHI study which does have methodological flaws, but unopposed estrogen is a no-no for patients with a uterus.

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