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Re:Ketamine no better than placebo at alleviating depression... by PragmaticPulp on Monday May 22, 2023 @09:30AM (#36031211)
> Of course you can argue they are not using enough K at the 0.5 mg/kg mark, because disccociation starts at 1 to 3 mg/kg

Dissociation isn’t necessary for the antidepressant effect, according to studies. In fact, many of the more responsible clinics target longer duration, lower peak dose infusions for this reason.

Re:Ketamine no better than placebo at alleviating depression... by arthur2e5 on Tuesday May 23, 2023 @11:06AM (#36045362)
Well, yeah. But the parent comment is insisting that the spiritual bits is doing something, and I was just way too lazy to look for a dose response study.