Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans

Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by Broken_Hippo on Sunday May 07, 2023 @07:16AM (#35850224)

I'd think there were two ways to produce this.

The first would be to not disclose the dose. If you don't know the dose, you might just assume it is a low dose and you aren't getting effects. This is especially easy to pull off since a lot of folks know about microdosing - which usually has the goal of not-too-much-hallucination.

Second, you can get folks new to LSD in combination with the above.

I'd think that the issue with giving another drug is that we wouldn't know how that drug is going to affect the outcome. You still need the baseline of sober folks to compare to, and given them a fake dose means that the ones that will have the placebo effect, will.

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Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by throwaway50606 on Sunday May 07, 2023 @07:42AM (#35850364)

If you have any hallucinations at all, you're not microdosing. Microdosing is right before the tipping point of recognizing you took something at all. It should be recognizable from long-term effects, not immediately.

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Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by throwawayadvsec on Sunday May 07, 2023 @07:59AM (#35850474)

I wonder if there is more data about this.

A while ago I've microdosed 1 to 2g of fresh truffles(which should not induce a trip), a few days/weeks after a real trip, and I had some hallucinations, which should not have happened

IDK, is it possible that a microdose could trigger some kind of a release of a previous buildup of some hallucinogens?

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Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by petemir on Sunday May 07, 2023 @08:31AM (#35850774)

Doses seem to accumulate, that’s why you need days off, too, and they recommend not to mix macro and micro doses. I’ve read somewhere that after a big dose you should wait ~1 month for the effects to wean.

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Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by hackernewds on Sunday May 07, 2023 @08:18AM (#35850645)

from lots of experience, yes it can

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Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by hackernewds on Sunday May 07, 2023 @08:18AM (#35850638)

Micro dosing (as the name suggests) is more about the input dose, than the output results

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Re:Effect of lysergic acid diethylamide (LSD) on reinforceme... by throwaway50606 on Sunday May 07, 2023 @08:24AM (#35850707)

Not really, it is about achieving some effect with a specific dose. The effect is about some improvements in your life without tripping. If you're tripping, you're not microdosing.

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