Good question. There's obviously a line somewhere. But I think it's ultimately almost always down to what's technically achievable. Poverty causes suffering in so many ways. I don't think we'll every be able to fix all of them without fixing poverty itself. My point is not to make someone happy by medicating him with a drug causing him more harm. Suffering people already do that with actual "recreational" drugs. And we have a lot of data on the side effects of those substances and additional harm they do, not because they alleviate suffering, but because of all other effects they have.