A belief in natural emergence relies not only on endless untestable hypotheses, but even still results in the exact same sort of frustrating unanswerables. For instance if one believes that the initial matter, which would culminate in the Big Bang, whisked into existence through a quantum fluctuation, then it immediately leads to the question of what created this void, rich in quantum interactions, or the nature of quantum interactions themselves? And for that there's not even a hypothesis, untestable or not.

Maybe there will be one day, but also maybe not. To me the simplest answer is to simply acknowledge of our own inability to offer any compelling answer to this question. That's not to say an acceptance of such inability, but assuming the nature of a destination (one way or the other), in a journey we've yet to even scratch the surface of, seems neither simple nor wise.