There are mathematicians unhappy with the notion even while being well versed in the Cantor (and other) arguments.
You can wander down that rabbit hole via (say) [1] as a starting point.
[1] https://en.wikipedia.org/wiki/Constructivism_(philosophy_of_...
[0] Title of a paper by John Wheeler. Can't find it right now, but if you google "it from bit" you'll find a lot of commentary on it.
What does it mean for something to be a physical structure? That you perceive it to be physical? But aren't your perceptions part of the universe? So how would you know if it actually "exists" anywhere?
Space might appear "infinite" if you set up a word problem where you fire two photons off in opposite directions and track the distance between them over time, but without an observer the only place information exists is in those photons, and space is meaningless. Infinities of time are likewise artificial constructs of measurement, there is only the current moment.
Yes, it's very complex, but there's plenty of room in infinity.
It doesn't need to have a "real" physical instantiation anywhere. It's like the simulation hypothesis, except you don't need the simulation. We're just the inside of an infinite self-experiencing mathematical structure, with nothing on the outside.