Isn't this what most of science was built upon - Is he right or wrong? Sometimes a need for minds who can push ideas into scientific thinking.
If that wasn't the case, then we might not even have Quantum Physics as it is today...
Unlike medical cranks out there, Penrose has (far as I've seen) never said anything of this is definitive - only that there is the potential in his theory that Orch-OR is the likely seat of conciousness.
Sapolski's take on determinism was really a low blow for me, and I've since seen several other intellectuals I respect very highly espouse similar views, and there was a point where I would have agreed in my adolescence, but I've since then developed away from that course of thinking. I often wonder if it's a rationalization which is necessary for the framework of the theory of everything to be coherent.
But a quantum physicist would then ask "to what degree?" because quantum mechanics is very deterministic over large sample sizes (and a few trillion proteins in the brain would be a very large sample).
More importantly though, free will implies the ability to make a choice and that has problems when you invoke quantum indeterminacy to explain it: you don't get "a choice" you get random chance deciding things (and other depressing ideas like "human consciousness can't be backed up, saved or transferred - we really are trapped in these meat prisons and doomed to suffer).
And we've also got eyes, which in principal means that many life forms already have quantum-sensitive apparati, right? Magnetoreceptors as well, and they're also found in "lower lifeforms" in various different forms from the basest phototaxis to extraordinarily refined lens systems which can numerous wavelengths.
And then I suppose when talking in scale — what does it actually mean — to flip that coin when you've only got an N of one in reality.
Of course I would have to concede that I accept an element, even a large one of determinacy, but my experience also precludes the idea of it existing exclusively. I'm really just pattering away right now, frankly I know very little of quantum physics (nothing, really) it's just nice to know someone is willing to furnish a hypothesis contrary to what I believe is the consensus on the topic.
I'm good with that as Penrose is very clear where the uncontroversial science ends and the hot takes begin; he doesn't try to "peddle" anything. "Here is my hot take and this is the TRUTH" is something I have problems with, "here's my hot take a lot of people will disagree with, but I think it may be true because [...]" isn't; and is often even valuable even if the hot take turns out to be wrong, because it exposes shortcomings, omissions, or other things that are not yet entirely clear.
https://en.wikipedia.org/wiki/Roger_Penrose#Consciousness
He’s clearly a smart guy… but also has some hot takes.
(Zero judgement intended; only bringing this up as background context.)