For large codebases PyCharm is superior, as VS Code usually chokes in its JavaScript memory usage before PyCharm's Java. You need to load large symbol datasets in the memory and VS Code seem to be struggling with this.

PyCharm autocompletion, autoimport, red underline errors and type hinting tools are also better than in VS Code.

VS Code Jupyter Notebook integration as better. PyCharm tends to do very badly with complex notebooks.

Using both 5+ years.