I'm sure it's been mentioned somewhere already, but the "plixltris/TwitchAdSolutions" repo on Github has a working blocker that switches the steam to an ad-free 480p version for in-stream ads. I think it can block the pre-roll ones somehow or reduce them because i hardly see any. Personally I use the Ublock script they have.

And PurpleTV is a modified Android Twitch app that is just like Youtube (Re)Vanced. Obviously use with caution, with an account you don't have any personal info linked to, because unlike YouTube you are forced to log in to the Twitch App. Pretty sure the Gitlab "twitchmod/orange-tv" repo is the official source.