It is more challenging, but not as much as it was before the pandemic started. 5 years ago less than 1% of the companies were offering 100% remote positions. Nowadays I can say that, at least from my point of view, I find that at least 30% of the companies out there offer 100% remote positions. I think this number is going up as well (as well as hybrid, though).

Thankfully, 100% office work is less and less common.

Nevertheless the biggest advantage is (as usual): your skills. If you ace the interview, companies in general will want to hire you no matter what.