qutebrowser has support for host-based blocking, which is better than nothing but a far cry from element blocking like UBlock Origin does. For me, qutebrowser's ad-blocking is pretty hit-and-miss, which is why I'm longing for UBlock Origin haha.
Origin is hard to beat and unfortunately a must have nowadays.
Although I must admit for a longer while I've been ignoring sites that are annoying or unusable without a blocker and it made my day much calmer. I stopped even clicking links on most "news" sites that are just borderline clickbaits.
Tried it before, long long time ago, but found it to complex. But now after using Vimium for a while Qutebrowser actually seems very intuitive and not hard at all.