Simulation of tsunami from dinosaur-killing asteroid that brought 2.5 mile waves

Re:Simulation of tsunami from dinosaur-killing asteroid that... by nextos on Tuesday February 07, 2023 @01:09AM (#34689343)

This is so true. Heavy-tailed distributions and extreme value theory [1,2] should be taught more widely.

The normal distribution is just a very particular case of the generalized CLT.

For example, some drug effects are heavy-tailed, but safety trials are often ignoring this.

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Re:Simulation of tsunami from dinosaur-killing asteroid that... by buryat on Tuesday February 07, 2023 @01:39AM (#34689520)

> some drug effects are heavy-tailed

where can i read about this? curious

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Re:Simulation of tsunami from dinosaur-killing asteroid that... by cosmojg on Tuesday February 07, 2023 @03:58PM (#34699509)

Got any sources which discuss the heavy-tailed effects of drugs and how they're ignored by safety trials? I'd love to read more!

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Re:Simulation of tsunami from dinosaur-killing asteroid that... by nextos on Wednesday February 08, 2023 @03:46AM (#34705704)

I don't have references with me right now, but there are quite a few reputable studies that have found effects to be log-normal.

Log-normal is a quite nasty heavy-tailed distribution as it's easy to take it for normal if you have small sample sizes.

This has tricked the safety calculations of a few trials. I don't think it's too worrying or generalized, just some area to improve.

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