Mefloquine seems much more notable for adverse neuropsychological side effects.

This was a big worry for me around ten years ago, when travelling to Africa while suffering from an anxiety/panic disorder. I was desperate to avoid taking anything that could make it worse. Doxycycline seemed like the safest choice at the time (and the cheapest!)

I was going to guess that drug too:

https://www.cbsnews.com/news/some-us-troops-haunted-by-anti-...

https://www.mayoclinic.org/drugs-supplements/mefloquine-oral...

I thought malarone was safer...

https://www.drugs.com/sfx/malarone-side-effects.html

Bingo!