When I had refractory major depression it felt like a terminal illness. I often hoped I'd get hit by a car or someone would kill me in a mugging. When you're depressed, people also often treat you like you have leprosy. However, now I struggle to empathize with others who are going through the same thing.

Thankfully I found medication and life changes that worked, especially moving to a sunny climate. I also recommend sobriety, it stops a vicious cycle with depression and dependence.