We have decades of research on this. Rates of desistence are low. Rates of regret are low, and are lower than most other forms of medical care.

Edit: Even the submitted article admits that on one side you have medical opinion and science saying PBs are safe and reversible, but that you have Republican politicians saying they're harmful. It doesn't present any evidence that PBs are harmful. I notice that you haven't either.

And anti-trans campaigners can't, because their position is incoherent. PBs are apparently so dangerous we can't give them to children, but children who've had them are still so powerful we can't allow them to compete in sports because they'd win everything.