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Re:A gut-derived hormone suppresses sugar appetite/regulates... by CharlesW on Sunday November 13, 2022 @10:56AM (#33584169)
> Most people can get an off-label metformin prescription for anti-aging.

Dumb question: How? I'm reasonably certain my GP would not be amenable to being asked to prescribe drugs for off-label use.

Re:A gut-derived hormone suppresses sugar appetite/regulates... by gruez on Sunday November 13, 2022 @11:03AM (#33584247)
Off label use is fine. I'd be more worried about the fact that a patient is bring it up out of the blue (ie. "give me drugs plz"), and the evidence for life extension is shaky

>There is some evidence metformin may be helpful in extending lifespan, even in otherwise healthy people. It has received substantial interest as an agent that delays aging, possibly through similar mechanisms as its treatment of diabetes (insulin and carbohydrate regulation). This is controversial, and an area of active research.[61][62]

Re:A gut-derived hormone suppresses sugar appetite/regulates... by bugfix-66 on Sunday November 13, 2022 @11:07AM (#33584288)
Just ask your doctor for it. Say: "Please prescribe me Metformin, 2 grams daily."

If you're overweight, tell your doctor you want help with your appetite. Otherwise, say you want metformin for its cancer prevention and anti-aging effects.

Metformin is safe and it almost universally improves health and well-being.

Your doctor knows this, and she'll gladly prescribe it.

Re:A gut-derived hormone suppresses sugar appetite/regulates... by dylan604 on Sunday November 13, 2022 @12:02PM (#33584901)
> Your doctor knows this, and she'll gladly prescribe it.

If your doctor gladly prescribes anything you just walk in and ask for by name and dosage and doesn't have a green cross symbol outside their office, then I'd highly suggest seeking out a new doctor.

Re:A gut-derived hormone suppresses sugar appetite/regulates... by bugfix-66 on Sunday November 13, 2022 @12:23PM (#33585102)
We're talking about a particular drug here (metformin) not just "anything".

I'm saying it's likely your doctor will be willing to prescribe METFORMIN (that drug, in particular) for off-label use if you ask.