Mocking senior American government officials is the most protected speech in the country, in fact. I do it liberally an encourage others to. It's the most fundamental part of holding them accountable.
Alicia Keys or Keri Hilson she ain't....
If she were an absentee First Lady and less proactive, I could totally see someone calling her "Sasquatch" (a big mythical ape-creature rarely captured on camera) as a criticism and I'd be ok with that.
Babylon Bee attacked a high-profile trans public servant in a way meant to (IMO) provide commentary on society's approach to trans issues and the implications for biological females? I'm ok with that too. I think some comedian, maybe Bill Burr or Andrew Schulz, had a similar bit: "Men are so awesome we're even better at being women than actual women. That's why a Man[Bruce Jenner] is Woman of the Year[Caitlyn Jenner], in his first year as a woman." or something to that effect.
My hot take is that it's OK to mock senior government officials, actually.