Work with your school's career center. They should be running career fairs and maintaining relationships with local companies and alumni affiliated companies that will help your resume get screened.

It helps if you have a personal project to highlight on the resume and discuss in interviews. But if you don't, highlight an interesting school project.

If you're graduating soon, you're also graduating into a downturn, so you're going to have to work harder to get started. Keep an eye out for good work in your field, but also look for other stuff where you can build up experience in a workplace, even if it's just office work.