Why is this being downvoted? HPC isn't jupyter notebooks on a workstation. I wish the 100GB output files (per timestep, some of my simulations produced 100+ of them) could fit on a jupyterhub instance because it would make life much easier.

Well the title is scientific computing, which includes HPC but not only. Anyway the fact is that a lot of "HPC" in university clusters is smaller jobs that are too much for an average PC to handle, but still fit into a single typical HPC node. These are usually the jobs that people think to farm out to AWS, but that you will generally find are cheaper, faster, and more reliable if you just run them on your own hardware.