Why are we not already using them? Because they're subQ injections? Supply issues? Side effects? They are already proven effective, why is every obese/overweight person not given a script? We could solve the crisis within a year

Before recently most GLP-1 agonists only gave a small amount of weight loss, and they've typically only been approved for type 2 management.

Mounjaro from Eli Lilly though shows great promise with an average weight loss of 50 pounds per participant. It's been approved for type 2 management, but they've also submitted it to the FDA as a weight loss drug.

On the first month on the lowest dose (no exercise), I lost 15 pounds.

The good side is the injection is mostly pain-free, and easy to administer. You will feel a little prick, but it feels mostly like getting a burr stuck to your skin.

The downside is it's $1000/month. Most insurance won't cover it yet. It also makes maybe more sense when insulin costs $5000/year or more. Right now there's a coupon which makes the co-pay $25 but that lasts for only 3 months.

Side effects for me were decreased appetite (which is a good thing), low level nausea, and constipation. All of which were not deal breakers for me.

They're injections, which reduces patient compliance, and they're peptides, which are costly to produce.

Yeah in the US we’d never curtail industrial food profit to overhaul the state of store shelves being full of easily consumed crap packaged in plastic waste of enormous energy and material cost.

The health side effects are not the only outcome of concern with our eating habits.