I don't go to a hotel to be in my room. If I am traveling there is a reason to do so.
All in all I think this paranoid fear of hotels and travel is something specific to US. I've never had issues with security in a hotel or even given it a a thought. In normal world you don't need to worry about this kind of stuff.
My biggest worry in hotel rooms these days is how to rig the A/C to stay on while I'm out.
Heated blanket on the thermostat? Or do they have timed-shutoffs or door-key based systems that cuts off the electricity when you leave? What do you do then?
Also AC is much more efficient if it keeps the room at a stable temperature rather than letting it heat up and then cooling it down again. I never set it that low myself but some hotels don't have a temp setting, that's true
If it were really overall more efficient it would be cheaper for the hotel owner to just keep it on all the time, but clearly it's not.
On the topic of flash floods esp. when traveling; I make a conscious effort to not park/stay anywhere liable to flash-flood, and that requires some situational awareness in the sense of at least knowing your surroundings and the area's geography/climate/seasonal weather patterns. We recently narrowly avoided getting caught in [0], and that was with us making a conscious effort to not spend too much time in any of the low-lying areas, not even for a day hike - we'd always park somewhere relatively high and simply avoided hiking any of the low regions. That storm happened just one day after we were there passing through that exact spot. The tourists staying at that popular hotel probably didn't think about how they're staying on the floor of an enormous desert valley in a monsoon-y time of year. By failing to prepare you're preparing to fail...
[0] https://www.latimes.com/california/story/2022-08-05/unpreced...